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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Linoleic Acid
drug:
Norepinephrine
Research Papers that Mention the Interaction
“Interestingly, the addition of LA to these cells induced the release of 5-hydroxytryptamine and noradrenalin to the extracellular environment.”
Linoleic Acid Induces Calcium Signaling, Src Kinase Phosphorylation, and Neurotransmitter Release in Mouse CD36-positive Gustatory Cells*“Similarly, chronic norepinephrine treatment in rats resulted in a net decrease in linoleic acid and an increase in arachidonic acid and docosahexaenoic acid, which was particularly pronounced when rats were fed an n-3 polyunsaturated fatty acid (PUFA)-rich oil diet.”
“ Linoleic acid enhanced the maximum responses to norepinephrine and adenosine without altering the ED50 values for these agonists.”
“ Linoleic acid markedly enhanced the stimulated formation of cyclic AMP by histamine and adenosine, as well that by norepinephrine , without affecting that by excitatory amino acids and veratridine.”
“The reactivity of isolated blood vessels to norepinephrine , angiotensin, PGE2 and PGA2 was intensified after linoleic acid free diet.”
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