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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Linoleic Acid and Masoprocol


Linoleic Acid



Research Papers that Mention the Interaction

Although NDGA was more inhibitory of cell growth in the presence of LA or CLA than INDO, growth was associated with both prostaglandin and leukotriene production.
Anticancer research  •  1997  |  View Paper
Nordihydroguaiaretic acid and high concentrations of indomethacin, each of which inhibits the lipoxygenase pathway of arachidonate metabolism, were effective in reversing the stimulatory effect of LA on MDA-MB-231 cell adhesion.
Nutrition and cancer  •  1995  |  View Paper
The inhibition by NDGA was reversed by arachidonic, linoleic , and oleic acids.
Endocrine research  •  2004  |  View Paper
Furthermore, nordihydroguaiaretic acid , a potent inhibitor of the lipoxygenase system, significantly reduced the growth-response effects of linoleic acid in VSMC, suggesting that conversion of linoleic acid to hydroperoxyoctadecadienoic acids (HPODEs) is required for these effects.
The Journal of clinical investigation  •  1995  |  View Paper
Nordihydroguaiaretic acid (80 microM) and alpha-tocopherol (100 microM) significantly decreased the cell death observed during incubations with AA or LA.
Clinical immunology and immunopathology  •  1992  |  View Paper
Incubation of soybean lipoxygenase and linoleic acid with p-aminophenol, catechol, hydroquinone, NDGA , or phenidone resulted in the formation of the one-electron oxidation products of these compounds.
Biochemistry  •  1989  |  View Paper