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Last Updated: 3 years ago

Possible Interaction: Linoleic Acid and Ghrelin

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supplement:

Linoleic Acid

drug:

Ghrelin

Research Papers that Mention the Interaction

“However, stearic acid, oleic acid, linoleic acid , and α-linolenic acid significantly suppressed octanoylated ghrelin production, with the effect of oleic acid being the strongest.”

Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production.

Journal of oleo science • 2015 | View Paper

“Prolonged (96 h), but not acute, treatment of the GHSR cells with the 18C OFAs oleic and linoleic acid caused a significant increase in sensitivity of the receptor to ghrelin (EC(50) reduced by a factor of 2.4 and 2.9 at 60 and 120 microM OFAs, respectively).”

Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization.

American journal of physiology. Endocrinology and metabolism • 2010 | View Paper

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