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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Linoleic Acid
supplement:
Fatty Acids, Omega-6
Research Papers that Mention the Interaction
“One mechanism for low linoleic acid , amenable to inhibition by docosahexaenoic acid, is increased metabolism in the n-6 fatty acid pathway.”
Lipid metabolism in cystic fibrosis“A diet providing a small amount of linoleic acid (0.6% to 1.3% of the total caloric intake) induced high levels of omega 6 fatty acid derivatives.”
“The presence of linoleic acid (low dose) produced a significant decrease in saturated and monounsaturated acids and an increase in 18:2, 20:4 and 22:5 n-6 fatty acids.”
Polyunsaturated fatty acid biosynthesis from [1-14C]20:3 n-6 acid in rat cultured Sertoli cells. Linoleic acid effect.“Dietary supplementation of linoleic acid increased n-6 fatty acid levels in lipids, whereas linolenic acid increased n-3 fatty acid levels.”
“Addition of linoleic acid to the culture medium for 48 h resulted in an approximate threefold increase in the amount of omega 6 fatty acids esterified to membrane phospholipids.”
“Results demonstrated that diets with higher concentration of omega-6 PUFAS induced an increment of linoleic and arachidonic acid on tumor cell membranes increasing ROS liberation, 12(S)-HHT generation, TP53, Ki67 expression and cell proliferation.”
Tumorigenic Effect Mediated by ROS/Eicosanoids and their regulation on TP53 expression in a Murine Mammary Gland Adenocarcinoma.
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