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Last Updated: 3 years ago

Possible Interaction: Linoleic Acid and Eicosatrienoic Acid

supplement:

Linoleic Acid

Research Papers that Mention the Interaction

The metabolism of linoleic acid seems to be disturbed with increased proportions of dihomo-gamma linolenic acid (20 : 3 n-6) and a reduced activity of the Δ5 desaturase, while the activities of the Δ9 and Δ6 desaturases appear to be increased.
British Journal of Nutrition  •  2000  |  View Paper
The ratio linoleic acid/dihomo-gamma-linolenic acid , reflecting the delta 6-desaturation and the following elongation step, increased with rising linoleic acid values.
Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit  •  1988  |  View Paper
A diet providing a large amount of linoleic acid (14% of the total caloric intake) resulted in low levels of dihomo-gamma-linolenic acid (C20:3 omega 6) and arachidonic acid (C20:4 omega 6) in serum phospholipids and cholesteryl esters.
Lipids  •  1985  |  View Paper
Stearic acid, a long-chain saturate, does not produce any reduction, whereas eicosatrienoic acid is an even more effective inhibitor than linoleic acid.
The Journal of clinical investigation  •  1981  |  View Paper
The conversion of linoleic into γ-linolenic acid and eicosatrienoic into arachidonic acid were mutually inhibited and the inhibition depended on the concentration of the fatty acids incubated.
Lipids  •  2006  |  View Paper
However, the desaturation of eicosa-8,11,14-trienoic acid is strongly enhanced by linoleic and γ-linolenic acids which may account for its non-accumulation in tissue lipids.
Biochimica et biophysica acta  •  1968  |  View Paper
Daily supplementation of either linoleic acid or linolenic acid were effective in suppressing the synthesis of 5,8,11-eicosatrienoic acid.
Biochimica et biophysica acta  •  1965  |  View Paper
The conversion of linoleic into 3' -linolenic acid and eicosatrienoic i n t o arachidonic acid were mutually inhibited and the inhibi t ion depended on the concentration of the fatty acids incubated.
Lipids  •  2006  |  View Paper
Supplementation of the essential fatty acid-deficient diet with linoleic acid caused a rapid loss of eicosatrienoic acid and palmitic acid with a concomitant increase in stearic acid and arachidonic acid.
The Biochemical journal  •  1965  |  View Paper