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Last Updated: 3 years ago

Possible Interaction: Lidocaine and Potassium

supplement:

Potassium

Research Papers that Mention the Interaction

High potassium raised calcium in control SH-SY5Y cells and those treated with articaine, but lidocaine treatment significantly reduced the response.
Anesthesia progress  •  2018  |  View Paper
The effect of potassium is reminiscent of its effect in the channelopathies underlying hypokalemic periodic paralysis, and the resistance to lidocaine applied peripherally suggests a peripheral sensory localization to the abnormality.
Journal of child neurology  •  2007  |  View Paper
Analysis of the single component effects showed that high potassium level, low sodium level, and the addition of lidocaine produced concentration-dependent vasoconstriction.
The Annals of thoracic surgery  •  1992  |  View Paper
In addition, prompt initiation of potassium infusion may dramatically resolve the arrhythmias, even if the serum potassium level is within the lower normal range, and may also potentiate the effect of class I antiarrhythmic drugs such as lidocaine.
Journal of cardiovascular pharmacology  •  1989  |  View Paper
Bupivacaine and lidocaine suppressed potassium currents.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova  •  2004  |  View Paper
Lidocaine (100 microM) attenuated the changes in membrane potential, sodium, potassium , ATP, and calcium during hypoxia.
Journal of neurophysiology  •  2001  |  View Paper
Both ischemia-induced sodium gain and potassium loss were significantly inhibited by lidocaine treatment.
Lidocaine (14.7 x 10 6 mol/L) significantly reduced the sudden increase of potassium in the first few minutes of reperfusion as well as its decline in the further course of reperfusion.
Journal of cardiovascular pharmacology  •  1988  |  View Paper
Lidocaine also significantly decreased the potassium loss and sodium gain occasioned by 2.5 h of glucose deprivation.
Anesthesiology  •  1982  |  View Paper
Lidocaine decreased the potassium conduction at the membrane potential values below--45 mW, and increased at--30 mW. Kinetic parameters of the rapid input sodium current and its amplitude significantly changed under the action of lidocaine in normal cardiac tissue, and its effect increased in the depolarized tissue.
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR  •  1981  |  View Paper
At all temperature levels lidocaine caused an additional reduction in the potassium efflux rate of about 50 per cent, probably by reducing membrane ion permeability in accordance with its local anesthetic action.
Anesthesiology  •  1981  |  View Paper
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