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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Lidocaine
supplement:
Oleic Acid
Research Papers that Mention the Interaction
“The addition of oleic acid (1% w/v) further enhanced lidocaine flux sixfold, in these formulations.”
Role of n-methyl pyrrolidone in the enhancement of aqueous phase transdermal transport.“The results indicate that among the FA-PG conjugates, oleic acid (C18:1n–9)-PG, linoleic acid (C18:2n–6)-PG and α-linolenic acid (C18:3n–3)-PG, mono- or di-esters, enhance the penetration of lidocaine relatively to the vehicle (without enhancer).”
Conjugates of Unsaturated Fatty Acids with Propylene Glycol as Potentially Less-Irritant Skin Penetration Enhancers“ Lidocaine specifically inhibited the incorporation of radioactive oleic acid into cellular cholesteryl ester but had no significant effect on the incorporation of oleic acid into phosphatidylcholine.”
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