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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Lidocaine and Oleic Acid


Oleic Acid

Research Papers that Mention the Interaction

The addition of oleic acid (1% w/v) further enhanced lidocaine flux sixfold, in these formulations.
Journal of pharmaceutical sciences  •  2005  |  View Paper
The results indicate that among the FA-PG conjugates, oleic acid (C18:1n–9)-PG, linoleic acid (C18:2n–6)-PG and α-linolenic acid (C18:3n–3)-PG, mono- or di-esters, enhance the penetration of lidocaine relatively to the vehicle (without enhancer).
Drug development and industrial pharmacy  •  2007  |  View Paper
Lidocaine specifically inhibited the incorporation of radioactive oleic acid into cellular cholesteryl ester but had no significant effect on the incorporation of oleic acid into phosphatidylcholine.
Archives of biochemistry and biophysics  •  1985  |  View Paper