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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Levonorgestrel
supplement:
Vitamin C
Research Papers that Mention the Interaction
“However, it is conceivable that the oral administration of gram quantities of vitamin C could also interfere with the sulfation of levonorgestrel (LNG) metabolites during phase II biotransformation, because sulfates represent a major part of the conjugated metabolites of LNG in the serum.”
Influence of high doses of vitamin C on the bioavailability and the serum protein binding of levonorgestrel in women using a combination oral contraceptive.
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