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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ L-DOPA failed to potentiate yohimbine effects; in fact it partially inhibited yohimbine.”
Exploration of the anti-depressant potential of L-DOPA“Once established, the enhanced behavioral response to repeated L-DOPA-administration (6.5 mg/… dyskinesia in man and MPTP-treated monkeys, be selectively reduced by coadministration of L-DOPA … yohimbine (10 mg/kg, -95%), the 5-HT uptake inhibitor 5-… beta-adrenergic receptor antagonist propranalol (10 mg/kg, -35%).”
Characterization of Enhanced Behavioral Responses tol-DOPA Following Repeated Administration in the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease“This potentiation was selectively antagonized by 1 nM L-dopa methyl ester, a competitive L-dopa antagonist, while yohimbine antagonized both the inhibition by UK14304 alone and its potentiation by L-dopa.”
“ Yohimbine antagonized the effects of L-DOPA , restoring the BP to near basal values within 5 min after i.v.”
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