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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Levodopa and Threonine

supplement:

Threonine

Research Papers that Mention the Interaction

Other neutral amino acids, such as alanine, asparagine, glutamine, serine, and threonine inhibited L-DOPA uptake by 40-70% at most.
Brain Research  •  2000  |  View Paper
L-DOPA increased nocturnal levels of Gly, Thr , Trp, and Val but had no effect on the daytime amino acids content.
Journal of biological rhythms  •  2000  |  View Paper
1000 mg/kg l-Dopa produced an even greater increase in the concentration of tyrosine and threonine in the liver as well as inducing a significant increase in hepatic-aspartic acid and serine.
Subcutaneous injections of 500 mg/kg l-Dopa daily for 8 days increased the concentrations of isoleucine, methionine, threonine and tyrosine.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1974  |  View Paper