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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Treating parkinsonian rats twice daily with levodopa induces many of the characteristic features of the human motor complication syndrome and further increases the serine and tyrosine phosphorylation of specific NMDA receptor subunits.”
Antiparkinsonian and antidyskinetic activity of drugs targeting central glutamatergic mechanisms“The treatment with L-dopa + AAID significantly decreased both CL and SER of "de novo" parkinsonian patients.(ABSTRACT TRUNCATED AT 250 WORDS)”
“Other neutral amino acids, such as alanine, asparagine, glutamine, serine , and threonine inhibited L-DOPA uptake by 40-70% at most.”
The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier“1000 mg/kg l-Dopa produced an even greater increase in the concentration of tyrosine and threonine in the liver as well as inducing a significant increase in hepatic-aspartic acid and serine.”
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