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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Levodopa
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“In six studies of five patients, including 7- to 8-h control and test periods, oral L-dopa … as long as 4 h. In seven of eight patients with medullary thyroid carcinoma (three infused with calcium …), L-dopa inhibited to varying degrees peak levels … by an average of 50%.”
The effects of L-dopa on in vitro and in vivo calcitonin release from medullary thyroid carcinoma.“Cell incubation with l-DOPA increased the vesicle CA content of WT but not of the CgB-KO cells.”
Chromogranin B Gene Ablation Reduces the Catecholamine Cargo and Decelerates Exocytosis in Chromaffin Secretory Vesicles“By parallel microdialysis in bilateral nucleus tractus solitarii areas, the basal L-DOPA release was in part inhibited by tetrodotoxin perfusion (1 microM) or Ca2+ deprivation, and was markedly reduced by alpha-methyl-p-tyrosine (200 mg/kg, i.p.),”
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