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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Levodopa and Ascorbate

supplement:

Ascorbate

Research Papers that Mention the Interaction

However, autoxidation reactions of L-DOPA may play a role since ascorbate suppressed the anti-catalase effect of L-DOPA.
Neurochemistry International  •  1996  |  View Paper
Reduced glutathione, ascorbate , superoxide dismutase, and catalase prevented the effect of levodopa and dopamine on complex I. Various inhibitors of monoamine oxidase also prevented the effect of dopamine.
Annals of neurology  •  1993  |  View Paper
Ascorbate supplementation did not alter establishment of experimental B16-BL6 melanoma metastases but inhibited tumor outgrowth when combined with LDME chemotherapy and the restricted diet.
The American journal of clinical nutrition  •  1991  |  View Paper