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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Levocarnitine
drug:
Stavudine
Research Papers that Mention the Interaction
“Thus, short-term incubation with high concentrations of d4T can rapidly induce accumulation of neutral lipids within rat hepatocytes, which can be fully prevented by l-carnitine.”
High concentrations of stavudine impair fatty acid oxidation without depleting mitochondrial DNA in cultured rat hepatocytes.“Studies show that d4T and ddI may cause neuropathy by lowering L-acetyl-carnitine levels; however, there have been no controlled studies showing that L-acetyl-carnitine therapy is effective.”
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