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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Levocarnitine and Olanzapine

supplement:

Levocarnitine

Research Papers that Mention the Interaction

Also, olanzapine markedly inhibited L-Car uptake in MDCK-hOCTN2 cells (1.06 µM of IC50), HepG2 cells and primary mouse hepatocytes.
Olanzapine treatment also reduced hepatic β-hydroxybutyrate level (indicator of fatty acid β-oxidation), meanwhile, the L-carnitine (L-Car) concentration in liver of olanzapine group was significantly lower than that in control group.
Supplementation of L-Car attenuated hepatic TG rise and improved simple steatosis in olanzapine treatment mice.
Toxicology letters  •  2019  |  View Paper