Possible Interaction: Levocarnitine and Long Chain Fatty Acid

“A number of observations have underlined the importance of L-carnitine in intestinal homeostasis, since it plays a key role in cell metabolism by regulating the mitochondrial transport of long-chain free fatty acids and the generation of adenosine triphosphate by b-oxidation.”

“ L-carnitine , a naturally occurring enzymatic antioxidant, is a necessary factor in the utilization of long chain fatty acids to produce energy.”

“It is well known that L-carnitine normalizes the metabolism of long-chain fatty acids in cases of carnitine deficiency.”

“ l-Carnitine plays a crucial role in uptake and subsequent β-oxidation of long-chain fatty acids in the mitochondria.”

“l-Carnitine LC ) plays an essential role in the β-oxidation of long-chain fatty acids in lipid metabolism.”

“ l-Carnitine and its ester, acetyl-l-carnitine (ALC), facilitate the transport of long chain free fatty acids across the mitochondrial membrane enhancing neuronal anti-oxidative defense.”

“Among these compounds, we concentrated our interest on L-carnitine (L-Cn), which regulates the beta-oxidation of long chain fatty acids necessary for brain development, myelinization and growth.”

“ L-carnitine (LC) plays an important regulatory role in the mitochondrial transport of long-chain free fatty acids (FFA).”

“In mechanically overloaded hearts, it has … the low tissue levels of L-carnitine , which regularly occur during the development of cardiac hypertrophy (WITTELS and SPANN 1968, … 1979, REIBEL et al 1983, BOWE et al 1984), may impair the long chain fatty acid utilisation (BISHOP and ALTSCHULD … and SPANN 1968).”

“ L-carnitine plays an important regulatory role in the mitochondrial transport of long-chain free fatty acids.”