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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Leukotriene D4
supplement:
Masoprocol
Research Papers that Mention the Interaction
“Peaks that migrated with authentic standards for LTB4, LTC4, and LTD4 were inhibited by the lipoxygenase inhibitor nordihydroguaiaretic acid.”
In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line.“In contrast, 5,8,11,14-eicosatetraynoic acid and nordihydroguaiaretic acid attenuated relaxation in response to leukotriene D4 and acetylcholine, suggesting that lipoxygenase-derived products may participate in leukotriene D4-induced as well as acetylcholine-induced relaxation.”
Endothelial‐Dependent Relaxation Induced by Leukotrienes C4, D4, and E4 in Isolated Canine Arteries“ NDGA had no effect on the contraction elicited by histamine but markedly inhibited the contraction elicited by LTD4.”
“Inhibitor treatment did not affect sensitivity or responsiveness of parenchyma to histamine, carbachol, and U-44069, but the contractile activity of LTD4 on both normal and sensitized lung parenchymal strips was reduced by indomethacin, NDGA , and phenidone.”
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