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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Leukotriene D4 and Genistein



Research Papers that Mention the Interaction

In addition, pertussis toxin and genistein , both known to interfere with the LTD4-induced calcium signal, completely or partially reversed the actin-depolymerising effect of LTD4.
European journal of cell biology  •  1998  |  View Paper
Genistein concentration-dependently relaxed histamine (30 microM)-, carbachol (0.2 microM)-, KCl (30 mM)- and leukotriene D4 (10 nM)-induced precontractions and inhibited cumulative histamine- and carbachol-induced contractions in a non-competitive manner.
Planta medica  •  2007  |  View Paper
Genistein , but not tyrphostin 47, significantly suppressed bronchial contraction to leukotriene D4 at 50 microM and to histamine at 100 microM. Daidzein, an inactive congener of genistein, did not alter OA-induced anaphylactic contraction.
The Journal of pharmacology and experimental therapeutics  •  1997  |  View Paper