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Last Updated: 3 years ago

Possible Interaction: Leukotriene C4 and Tretinoin

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drug:

Leukotriene C4

supplement:

Tretinoin

Research Papers that Mention the Interaction

“While LTC4 S mRNA and protein increased in the cells treated with RA , the co‐addition of ACD further potentiated both in proportion to the LTC4 S activity.”

Induction of leukotriene C4 synthase after the differentiation of rat basophilic leukemia cells with retinoic acid and a low dose of actinomycin D and its suppression with methylprednisolone

Journal of cellular physiology • 2003 | View Paper

“ Tretinoin , isotretinoin, retinol, retinal, and acitretin at 10(-5) M or 10(-4) M concentrations inhibited LTC4 release by A23187-stimulated horse eosinophils in vitro; 10(-4) M retinyl palmitate was also inhibitory.”

Retinoid-induced inhibition of eosinophil LTC4 production.

Prostaglandins • 1990 | View Paper

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