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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Leukotriene C4
supplement:
Genistein
Research Papers that Mention the Interaction
“All of these responses were concentration-dependently inhibited by genistein ; lavendustin A also exhibited potent inhibition of PAF-induced LTC4 release.”
Involvement of protein tyrosine kinases in activation of human eosinophils by platelet‐activating factor“ Leukotriene C4 and prostaglandin D2 production was blocked by genistein , a specific inhibitor of tyrosine kinases, and bisindolylmaleimide, a protein kinase C inhibitor, indicating a role for both phosphorylation pathways in the substance P-stimulated lipid mediator production.”
Substance P can stimulate prostaglandin D2 and leukotriene C4 generation without granule exocytosis in murine mast cells.
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