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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Leukotriene B4
supplement:
Linoleic Acid
Research Papers that Mention the Interaction
“The formation of LTB4 was dose dependently inhibited by both LA (IC50=45 μM) and DGLA (IC50=40μM).”
Linoleic acid and dihomogammalinolenic acid inhibit leukotriene B4 formation and stimulate the formation of their 15-lipoxygenase products by human neutrophilsin vitro. Evidence of formation of antiinflammatory compounds“ LA also increased the concentrations of cytokine-induced neutrophil chemotaxis (CINC-2αβ), tumor necrosis factor-α (TNF-α) and leukotriene B4 (LTB4), and reduced the expression of macrophage chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1 (MIP-1).”
Oral Administration of Linoleic Acid Induces New Vessel Formation and Improves Skin Wound Healing in Diabetic Rats
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