Possible Interaction: Leucine and Threonine

“RESULTS Le cine ba lances differed significantly (P = 0.02) between the different intakes of thr eonine. ”

“Substitution of a leucine by threonine in helix 8 of the ligand-binding domain of the zebrafish MR confers the antagonist response.”

“When a large dose of phenylalanine or threonine was administered, incorporation of the tracer leucine was significantly increased (from 0.036 to 0.”

“Plasma concentrations of essential amino acids, including threonine , methionine, isoleucine, valine, tyrosine, and phenylalanine were significantly decreased by leucine infusion.”

“The median (range) ΔHR between pre-intubation and intubation was higher (13.1%; - 4.3 to + 55.1) in group L (p = 0.0021).”

“Supplementation of leucine resulted in increased concentrations of glucose, methionine, threonine , histidine and EAAs and decreased concentration of arginine in serum.”

“Mutating the leucine at position 286 of the wild-type 5-HT3 receptor to threonine (i.e., mutant L286T) resulted in desensitization kinetics that were biphasic at all membrane potentials tested and with a rate of decay that was not voltage dependent.”

“ Threonine supplementation did not affect plasma methionine, tryptophan and(or) lysine, but it increased leucine (P less than .01) and isoleucine (P less than .05).”

“ Leucine was used as inhibitor of the transport of threonine , sarcosine, and lysine.”

“Phosphorylation of threonine destabilizes the leucine zipper of a bZIP protein by 4.6 kcal mol-1 dimer-1, which reduces DNA binding 100-fold.”