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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Leucine and Tamoxifen

supplement:

Leucine

Research Papers that Mention the Interaction

Megace alone and Megace plus tamoxifen significantly decreased both [3H]leucine incorporation into protein and tissue concentration of DHT; Megace plus ketoconazole significantly decreased L-[35S]methionine incorporation into protein and DHT.
Journal of steroid biochemistry  •  1986  |  View Paper
Further investigation revealed that tamoxifen inhibited unidirectional melphalan influx in human breast cancer cells both by the sodium-independent system L and by the sodium-dependent system ASC.
Biochemical pharmacology  •  1985  |  View Paper
We previously reported an improvement in disease free survival in women receiving extended adjuvant treatment with L after tamoxifen.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  2004  |  View Paper