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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Leucine
drug:
Simvastatin
Research Papers that Mention the Interaction
“The association of l -arginine with simvastatin could promote a further improvement on endothelial function in this condition.”
Effects of Simvastatin and l -arginine on Vasodilation, Nitric Oxide Metabolites and Endogenous NOS Inhibitors in Hypercholesterolemic Subjects“ Simvastatin inhibited the increase of NA‐induced increase of RNA content and [3H]‐leucine incorporation in a concentration‐dependent manner.”
Simvastatin inhibits noradrenaline‐induced hypertrophy of cultured neonatal rat cardiomyocytes“We treated neonatal rat cardiac myocytes with angiotensin II (AngII) with and without simvastatin (Sim) and found that Sim decreased AngII-induced protein content, [3H] leucine uptake, and atrial natriuretic factor (ANF) promoter activity.”
“Compared to TRP, LEU exhibited better protection of spray-dried amorphous SV from re-crystallization, which could be attributed to the formation of a LEU crystalline shell covering SV upon the spray drying process.”
Amino acids as stabilizers for spray-dried simvastatin powder for inhalation.
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