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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Leucine
drug:
Sildenafil
Research Papers that Mention the Interaction
“In animal studies, when combined with leucine , hepatic steatosis improvements were noted, and further addition of sildenafil synergistically enhanced these effects by further stimulating Sirt1 and improving liver histology.”
Editorial: role of leucine‐metformin‐sildenafil combination in the treatment of nonalcoholic fatty liver disease (NAFLD)“Results The combination of l -arginine and sildenafil produced a significant dose-dependent increase in left anterior descending flow and cardiac output.”
Combined Intravenous Sildenafil and l-Arginine Administration in a Porcine Animal Model: Hemodynamic Safety Profile and Effects on Coronary Blood Flow“ Sildenafil dose-dependently blocked L-type Ca(2+) current (I(Ca, L )), but had no effect on persistent Na(+) current in guinea pig ventricular myocytes.”
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