supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Leucine
drug:
Propranolol
Research Papers that Mention the Interaction
“For propranolol , total clearance (44.3 ± 15.9 L h−1) and volume of distribution (230.5 ± 48.2 L or 2.7 ± 0.7 L kg−1) were significantly less than control values.”
Comparison of Propranolol and Sotalol Pharmacokinetics in Obese Subjects“Increases in VFT produced by addition of L to metoprolol and propranolol were synergistic (metoprolol > propranolol) and significantly greater than increases obtained after administration of these drugs alone.”
Effects of Metoprolol, Alone and in Combination with Lidocaine, on Ventricular Fibrillation Threshold: Comparison with Atenolol, Propranolol, and Pindolol“This can be supported by … facts that treatment with propranolol , 10 or 30 mg/kg, reduced release of cathepsins B, L and D from lysosome to cytosol in the ischemic tissue and that the reduced acidity of the ischemic tissue was improved by treatment with propranolol, 30 mg/kg.”
“In the short-term experiment, most individual amino acids were increased in T3-treated rats, also if beta-blocker had been given, but the increase in plasma concentration of some amino acids (valine, leucine , lysine and histidine) was prevented by propranolol.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback