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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Leucine
drug:
Propafenone
Research Papers that Mention the Interaction
“A range of propafenone concentrations were applied which reduced ICa, L in a dose‐dependent manner (IC50 1.7 μM).”
“Also, the recovery of ICa, L from inactivation was slowed by propafenone.”
“In the presence of propafenone , the voltage‐dependence of inactivation of ICa, L was shifted 8 mV in the hyperpolarizing direction.”
“When test pulses were applied to a range of potentials, propafenone reduced ICa, L at each potential without significantly affecting the activation curve for this current.”
Inhibition of L‐type calcium current by propafenone in single myocytes isolated from the rabbit atrioventricular node
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