Possible Interaction: Leucine and Penicillins

“It is now known that infection with the L phase of bacteria occurs commonly in man, and furthermore, that the L form can occur spontaneously without induction by antibiotics, although penicillin has greatly increased its incidence.”

“The alterations in morphology, osmotic stability, growth rate, and nutritional requirement which the bacteria have sustained as a result of their conversion to the L form can therefore all be attributed to reversible inhibitory effects of penicillin on genetically unaltered cell populations.”