Possible Interaction: Leucine and Norepinephrine

“ Norepinephrine uptitration significantly increased cardiac index (2.….5 to 2.8 ± 0.1 L · min−1 · m−2 ), cardiac power index (0.40 ± 0.1 to 0.55 ± 0.1 W/m2), mixed venous … (69% ± 9% to 73% ± 9%), and coronary perfusion pressure (32 ± 3 to 43 ± 4 mmHg).”

“Finally, norepinephrine , isoproterenol, CL316243, and palmitate inhibited the effects of insulin, L-leucine , and L-glutamate on leptin synthesis.”

“Whole‐cell voltage‐clamp recordings showed that 1 μM noradrenaline increased both ICa, L and ICl(Ca), but it had no significant effect on the principal K+ currents.”

“Values of maximum active stress with smooth muscle activation by 75 mM K+ plus 10 microM norepinephrine were significantly higher at 24 and 36 wk in O (at 36 wk: L = 573 +/- 42 and O = 821 +/- 89 x 10(3) dyn/m2).(ABSTRACT TRUNCATED AT 250 WORDS)”

“Endogenous NE concentration was significantly reduced 45 min after L -dopa despite high levels of dopa and DA.”

“… L:… noradrenaline at the three different times of the day compared with those acclimated to 16 h:8 h L:D. The extent of the response … suggest that photoperiod is an important cue for seasonal acclimatization in this species and that the response to noradrenaline follows a daily rhythm.”

“This stimulation could be blocked by either cycloheximide or actinomycin D, and norepinephrine stimulation was also blocked by L -propranolol.”