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Last Updated: 2 years ago

Possible Interaction: Leucine and NADH

supplement:

Leucine

supplement:

NADH

Research Papers that Mention the Interaction

The leucine substitution at residue 275 was found to significantly decrease the affinity towards the physiological reducing substrate, NADH , without affecting the activity of the P275L variant.
Archives of biochemistry and biophysics  •  2006  |  View Paper
The effects of GTP and 2-oxoglutarate in potentiating inhibition by NADH can account for their effects in enhancing the apparent activation by L-leucine.
Biochimica et biophysica acta  •  1989  |  View Paper
These results indicate that beta cell metabolism of monomethyl succinate and leucine , like glucose, influences dehydrogenases that produce NADH.
Archives of biochemistry and biophysics  •  1989  |  View Paper
Leucine also stimulated mitochondrial biogenesis genes SIRT-1, PGC-1α and NRF-1 as well as mitochondrial component genes UCP3, COX, and NADH expression by 3–5 fold in C2C12 cells (p < 0.003).
Nutrition & metabolism  •  2009  |  View Paper
The uptake rates of K(+), 3-O-methylglucose, leucine , and arginine were all decreased in the presence of NADH.
Plant physiology  •  1985  |  View Paper