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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Leucine and Lidocaine

supplement:

Leucine

Research Papers that Mention the Interaction

Increasing concentrations of lidocaine in the incubation medium inhibited the uptake of methyl alpha-D-glucoside (IC(50) approximately 3.5 mmol/L) and L-leucine (IC(50) approximately 6 mmol/L) in a dose-dependent manner.
Uptake kinetics of methyl alpha-D-glucoside and L-leucine in the presence of lidocaine revealed a significant increase in the apparent Michaelis constant, leaving the maximal transport capacity essentially unaltered.
Biochemical pharmacology  •  2000  |  View Paper