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“ L-leucine decreased the intestinal absorption of levodopa from 40 +/- 19 to 21 +/- 15% but was without effect on the absorption of antipyrine, benserazide and D-glucose.”
British journal of clinical pharmacology • 1993 | View Paper
“High-protein meals or oral phenylalanine, leucine , or isoleucine (100 mg per kilogram of body weight) reversed the therapeutic effect of infused levodopa without reducing plasma levodopa concentrations.”
The New England journal of medicine • 1984 | View Paper
“Incubation of MBH in Krebs-Ringer solution with l-leucine , a competitive inhibitor of l-DOPA uptake, was used to prevent a hypothetical l-DOPA capture into AADC-containing neurons.”