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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Leucine and Glutamate

supplement:

Leucine

supplement:

Glutamate

Research Papers that Mention the Interaction

L-Leucine slightly decreased the rate of L-glutamine deamidation, inhibited the conversion of glutamate to 2-ketoglutarate by transamination, increased the oxidative deamination of L-glutamate , stimulated the recirculation of 2-ketoglutarate to glutamate and inhibited the further oxidative metabolism of 2-ketoglutarate.
The Journal of biological chemistry  •  1982  |  View Paper
The synthesis of carboxylase and lyase appeared to have been repressed by the addition of l-glutamate or glucose to cells growing on dl-leucine as the sole carbon source.
Journal of bacteriology  •  1974  |  View Paper
On the other hand, L-glutamate induced the enzyme synthesis; L-isoleucine, L-leucine and L-valine also increased it.
Journal of general microbiology  •  1968  |  View Paper