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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Leucine and Dihydrotestosterone

Research Papers that Mention the Interaction

The combination of Ph + F reduced yields by 2.7-fold compared with Ph alone and Ph + L reduced DHT synthesis by 2.4-fold compared with Ph alone (n = 6; P < 0.001).
Journal of clinical periodontology  •  2002  |  View Paper
L inhibited DHT synthesis from both substrates by 36-38%, with further inhibition of 55-70% (n = 4; p < 0.01), with P; this is suggestive of ligand-independent alkaline phosphatase activity mediated by 5 alpha-reductase.
Journal of periodontal research  •  2000  |  View Paper
Likewise, epithelial cell incorporation of [3H]leucine into protein correlated significantly with tissue DHT concentrations, with a r value of 0.79.
The Journal of clinical endocrinology and metabolism  •  1985  |  View Paper
Renal TMPRSS2, furin, and cathepsin L were upregulated by DHT and differentially modulated by the diet.
International journal of molecular sciences  •  2021  |  View Paper