Possible Interaction: Leucine and Cupric Cation

“Furthermore, compound L formed a 1:1 complex with Cu2+ and the binding constant between sensor L and Cu2+ was high at 6.02 × 104 M-1 .”

“The result of anticancer activity studies show that the cytotoxic activity of L against MCF-7 and HeLa cells is increased, when chelated with Cu(II).”

“The chemosensor L displays an "on-off-on" response type fluorescence change upon the addition of Cu2+ and S2- to aqueous media and living cells.”

“When the probe L interacted with Cu2+ , the color and the fluorescent intensity changed obviously and it provided the naked-eye detection for Cu2+.”

“… L) … Cu(II) salts (p-toluenesulfonate, benzoate and o-, m- or p-hydroxybenzoate) led to the formation of [Cu(p-SO3C6H4CH3)L(H2O)2](p-SO3C6H4CH3) (1), [… characterized by elemental and TG-DTA analyses, ESI-MS, IR spectroscopy and single crystal X-ray diffraction, as well as by conductivimetry.”

“ L in the presence of Cu(II) , in an inert atmosphere, results in a reductive cleavage of the disulfide bond and an in situ formation of a new C-S bond.”

“The strong and selective coordination of L with metal ions (Zn2+, Cu2+ and Fe3+) separates the NTPC from the AgNPs surface that turn-on the NTPC fluorescence.”

“ L shows different behavior in Cu(II) and Zn(II) binding, affecting the dinuclear species formed and the distance between the two coordinated metal ions, which is greater in the Zn(II) than in the Cu(II) dinuclear species.”