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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Leucine and Cisapride

supplement:

Leucine

Research Papers that Mention the Interaction

Cisapride also delayed the kinetics of recovery of I(Ca, L ) from inactivation.
Cisapride elicited a tonic block and a use-dependent block of I(Ca, L).
The inhibitory effect of cisapride on I(Ca, L ) might play an important role in its cardiotoxicity under pathophysiological conditions, such as myocardial ischemia.
These blocking effects were voltage dependent as the degree of inhibition at -40 mV was greater than that at -70 mV. Cisapride shifted the steady-state inactivation curve of I(Ca, L ) in the negative direction, but had no effect on the steady-state activation curve.
Journal of biomedical science  •  2004  |  View Paper