Possible Interaction: Leucine and Calcium Supplement

“Dietary Ca was, however, oversupply in L compared with C diets (3.1 v. 2.5 Ca:digestible P ratio, respectively) suggesting that P has probably driven the regulations.”

“These results suggest that enhancement of INa L alters calcium cycling.”

“Action potential-evoked Ca2+ influx via either L or N type Ca2+ channels triggers CICR.”

“Averaged over sampling times … interaction, P < .10), both L and … Ca and Na concentrations on d 91 and 119 compared with C. Serum inorganic P was increased (P < .10) for … ionophore treatments compared with C (P < .10) on several occasions (treatment x day x sampling time interaction, P < .05).”

“All these results are … with a hypothesis that calcium plays a critical role in determining the kinetics of calcium release during both L and P. An important component seems to be the entry of external calcium, which sets the stage for calcium release by loading up the internal stores.”

“A high dietary content of calcium (25.9 vs 11.8 g/kg) reduced chick performance and the digestibility of glutamic acid, leucine and phenylalanine but increased the digestibility of lysine and histidine.”

“In vitro studies demonstrated that the addition of 1 mmol calcium to 1 L of a 200 mM bicarbonate solution raised the PCO2 by approximately 50 mmHg (1 mmHg = 133.322 Pa).”

“The rate of release of accumulated leucine was affected to a much lesser extent by the presence of calcium.”

“ Calcium in concentrations ranging from 0.01 to 4.0 mM increased the incorporation of leucine into proteins of...”

“ Calcium stimulates leucine incorporation into protein during incubations of sections and cell-free preparations of the rat adrenal.”