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“These results suggest that alpha1-adrenergic stimulation enhances cardiac ICa, L and that obligatory intracellular mediators for this action are lost during whole cell recordings.”
The American journal of physiology • 1998 | View Paper
“Our results demonstrate that ICa L can be enhanced by alpha1-adrenergic stimulation , and stress the importance of not disturbing the intracellular environment during studies of the modulation of cardiac ICa,L by alpha1-adrenergic stimulation.”