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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Leucine
supplement:
3-Hydroxykynurenine
Research Papers that Mention the Interaction
“With hepatocytes from animals fed on the low-tryptophan, niacin-free control diet, the addition of leucine to the incubation medium resulted in reduced synthesis of niacin from tryptophan, and a small increase in the accumulation of 3-hydroxykynurenine.”
Effects of a dietary excess of leucine and of the addition of leucine and 2-oxo-isocaproate on the metabolism of tryptophan and niacin in isolated rat liver cells.
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