“ Lentinan (2.5 μg/mL) plus low‐dose miltefosine (2 μM) displayed heightened level of pro‐inflammatory cytokines, IL‐12 (13.6‐fold) and TNF‐α (6.8‐fold) along with nitric oxide (7.2‐fold higher) when compared with infected control.”
“The in vitro interaction between lentinan and miltefosine showed some synergy (mean sum of fractional inhibitory concentration [mean ∑FIC] 0.87) at IC50 level.”