Possible Interaction: Lecithins and Phospholipids

“In fibrins of all groups the percentage of lecithin was significantly increased indicating a participation of plasmatic phospholipids.”

“ Phosphatidyl-choline , the principle phospholipid of surfactant in normals, was reduced in all three groups of patient when expressed as a percentage of total phospholipids.”

“However, lecithin significantly reduced total lipids, increased the relative concentration of phospholipid and tended to increase the phospholipid/free cholesterol (PL/FC) concentration.”

“In the deficient group, PC metabolism showed an increased incorporation of [14C methyl] choline in choline phospholipids but decreased incorporation in phosphoryl choline in comparison with the casein group.”

“The addition of lecithin to rat diet significantly increased phospholipid concentration (p < 0.05) compared with controls.”

“During continued triglyceride secretion in the presence of lecithin , the phospholipid : unesterified cholesterol ratio of the chylomicrons increased significantly in contrast to lecithin-free emulsions.”

“… lecithins … phospholipids that were inactive or scarcely active per se, such as phosphatidylethanolamine and lysophosphatidylcholine (miristoyl; Iysod 14 ) increased the activating efficiency of lecithins, (b) ApoHBD …-water interface was not essential for HBD activity since a molecular dispersion of diheptanoyl lecithin (diC 7 ) activated apoHBD to a limited extent.”

“Fractionation of plasma phospholipids at 24 h revealed lecithin increased to 68% of total phospholipid (control 46%), and lysolecithin decreased to 12% (control 25%).”

“in the absence of phospholipids , less than 10% oxidation occurs in the presence of the lecithins.”