supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Lecithins
drug:
Deoxycholate
Research Papers that Mention the Interaction
“After administration of mangiferin at a dose of 30 mg/kg combining with sodium deoxycholate, the bioavailability of mangiferin increased four-fold, and this may be due to sodium deoxycholate weakening the compactness between lecithin molecules and increased the paracellular permeability.”
Increased absorption of mangiferin in the gastrointestinal tract and its mechanism of action by absorption enhancers in rats“From zeta-potential measurements, it is evident that lecithin affects the partition of bile salts, most probably by displacing deoxycholate molecules.”
“It was found that lecithin and the detergents used ( deoxycholate and sodium dodecylate) inhibited the renin activity.”
“Mg2+, deoxycholate and albumin enhanced the enzymatic activity against lecithin , while Ca2+, Zn2+ and ethylendiaminetetraacetate inhibited the activity.”
Properties of purified phospholipase C from Acinetobacter calcoaceticus.“Vogel & Zieve (1960), working with the phospholipase A of human duodenal contents, also obtained evidence of activation of the hydrolysis of lecithin by deoxycholate.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback