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Last Updated: 2 years ago

Possible Interaction: Lecithins and Deoxycholate

supplement:

Lecithins

Research Papers that Mention the Interaction

After administration of mangiferin at a dose of 30 mg/kg combining with sodium deoxycholate, the bioavailability of mangiferin increased four-fold, and this may be due to sodium deoxycholate weakening the compactness between lecithin molecules and increased the paracellular permeability.
Drug development and industrial pharmacy  •  2013  |  View Paper
From zeta-potential measurements, it is evident that lecithin affects the partition of bile salts, most probably by displacing deoxycholate molecules.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology  •  1997  |  View Paper
It was found that lecithin and the detergents used ( deoxycholate and sodium dodecylate) inhibited the renin activity.
Acta biochimica Polonica  •  1976  |  View Paper
Mg2+, deoxycholate and albumin enhanced the enzymatic activity against lecithin , while Ca2+, Zn2+ and ethylendiaminetetraacetate inhibited the activity.
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology  •  1972  |  View Paper
Vogel & Zieve (1960), working with the phospholipase A of human duodenal contents, also obtained evidence of activation of the hydrolysis of lecithin by deoxycholate.
The Biochemical journal  •  1964  |  View Paper