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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Lauric Acid
Research Papers that Mention the Interaction
“On the other hand, the intestinal absorption of thyrotropin releasing hormone (TRH), which is transported by a carrier-mediated process, was also enhanced by chemical modification with lauric acid.”
[Improvement of intestinal absorption of peptide and protein drugs by chemical modification with fatty acids].“The binding amounts of TRH to the BBM were remarkably enhanced by the lauric acid conjugation; however, its binding was nonspecific.”
“The penetration of TRH across the upper small intestine was significantly increased by conjugation with lauric acid.”
Enhancement of intestinal transport of thyrotropin-releasing hormone via a carrier-mediated transport system by chemical modification with lauric acid.“These findings indicate that chemical modification of TRH with lauric acid might be a useful approach for improving the intestinal absorption of this peptide.”
“These results suggest that chemical modification of TRH with lauric acid may not only increase the lipophilicity of TRH but also reduce the degradation of TRH, resulting in the increased plasma radioactivity of TRH.”
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