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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Latrepirdine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Here, we demonstrate that dimebon enhances the resistance of the isolated rat brain and liver mitochondria to the induction of mitochondrial permeability transition (MPT) by calcium ions even in the presence of atractyloside, a MPT pore (MPTP) opener, but is ineffective against atractyloside-induced mitochondria swelling.”
Dimebon attenuates the Aβ-induced mitochondrial permeabilization.“One putative mechanism underlying the neuroprotective properties of Dimebon is inhibition of mitochondrial permeability transition, based on the observation that Dimebon inhibited the swelling of rat liver mitochondria induced by calcium and other agents that induce permeability transition.”
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