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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Lamotrigine and Serum Albumin, Human

Research Papers that Mention the Interaction

Binding constant (Kb) of 5.74×103 and number of binding site of 0.97 showed that there is a slight interaction between lamotrigine and HSA.
lamotrigine … HSA in the studied concentrations was not as much as many other drugs, but the secondary structure of the HSA was significantly changed following the … α-helix percentage was reduced from 67% to 57% after the addition of lamotrigine in the molar ratio of 4:1 to HSA.
Journal of photochemistry and photobiology. B, Biology  •  2017  |  View Paper