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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Lamotrigine
supplement:
N-Acetylaspartate
Research Papers that Mention the Interaction
“Given that NAA is synthesized through direct acetylation of aspartate by acetyl-coenzyme A-l-aspartate-N-acetyltransferase, we hypothesized that treatment with lamotrigine would be associated with an increase in NAA level.”
N-acetylaspartate normalization in bipolar depression after lamotrigine treatment.“However, the N-acetylaspartate/creatine in rats pretreated with lamotrigine (10 mg/kg) (P < 0.01) and MK-801 (P < 0.05) still showed significant reduction as compared with sham controls.”
Neuroprotective effect of lamotrigine and MK-801 on rat brain lesions induced by 3-nitropropionic acid: evaluation by magnetic resonance imaging and in vivo proton magnetic resonance spectroscopy
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