“Co‐medication with carbamazepine, simvastatin, paracetamol, amiodarone, fluconazole, lactulose , or bezafibrate was associated with significant changes in dispensed warfarin doses , by +40%, −3.4%, −7.3%, −8.2%, −8.8%, −9.0%, and −9.7%, respectively.”
“Initiation or discontinuation of bezafibrate or lactulose in a patient on warfarin should warrant close clinical monitoring.”