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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The administration of lactulose causes a reduction in the urea production rate consistent with a reduced entry of ammonia into portal blood, but it does not appear to directly inhibit urea degradation.”
Effects of lactulose on nitrogen metabolism.“The administration of lactulose causes a reduction in the urea production rate consistent with a reduced entry of ammonia into portal blood, but it does not appear to directly inhibit urea degradation.”
“ Lactulose caused a 23% reduction in the urea production rate that was mainly accounted for by increase in fecal nitrogen excretion.”
“In our previous studies of cirrhotic subjects lactulose caused a 25% decrease in the urea production rate associated with a decrease in urinary urea excretion and an increase in stool nitrogen.”
“In previous studies with cirrhotic subjects administration of oral lactulose caused a reduction in the urea production rate associated with an increase in fecal nitrogen excretion.”
“Only lactulose caused a reduction in fecal pH. Magnesium sulfate had no significant effect on the urea production rate or urinary nitrogen excretion, whereas lactulose caused a 25% reduction in the urea production rate and an 18% reduction in urinary nitrogen excretion.”
“The change in urea production rate in response to lactulose therapy was an indirect measure of a reduction in total gut ammonia production.”
“ Lactulose caused a fall in urea production (-24%, P less than 0.005) that was reflected in a decrease in both urea degradation and urinary urea excretion.”
“The results indicate that: (a) Lactulose decreases urea production by increasing the fecal output of nitrogen, a finding compatible with altered ammonia metabolism by gut flora. (”
“ Lactulose led to particularly high transfer of urea and absorption of ammonia.”
Specific effects of fermentable carbohydrates on blood urea flux and ammonia absorption in the rat cecum.“Introduction: Lactulose is a prebiotic with bifidogenic and urea reduction effects.”
The effect of lactulose supplementation on fecal microflora of patients with chronic kidney disease; a randomized clinical trial“The administration of lactulose causes a reduction in the urea production rate consistent with a reduced entry of ammonia into portal blood, but it does not appear to directly inhibit urea degradation.”
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