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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Ketoconazole
supplement:
Vitamin K
Research Papers that Mention the Interaction
“ Ketoconazole elevated the plasma levels of vitamin K1 and increased the average area under the concentration‐time curve (AUCinf) and peak concentration by 41% and 40%, respectively.”
“This study revealed that ketoconazole and CYP4F2*3 polymorphism substantially increased the exposure of vitamin K1 in humans.”
Effects of Ketoconazole, a CYP4F2 Inhibitor, and CYP4F2*3 Genetic Polymorphism on Pharmacokinetics of Vitamin K1
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