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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ketanserin and Secretin

supplement:

Secretin

Research Papers that Mention the Interaction

Both the 5-HT(2) receptor antagonist ketanserin and the 5-HT(3) receptor antagonist ondansetron at 1-100 microg/kg dose-dependently inhibited acid-induced increases in plasma secretin concentration and pancreatic exocrine secretion.
Ketanserin or ondansetron at 10 microg/kg or a combination of both suppressed the pancreatic secretion in response to intravenous secretin at 2.5 and 5 pmol x kg(-1) x h(-1) by 55-75%, but not at 10 pmol x kg(-1) x h(-1).
American journal of physiology. Gastrointestinal and liver physiology  •  2001  |  View Paper